MBON screen progress 19.06.2026

on Monday, June 22nd, 2026 12:15 | by

MBON screen of MB399 for MBON02, MB050B for MBON15, MB027B for MBON17 all crossed with TnTe and WTB x TnTe for the negative control. Flies are tethered in torque meter and one turning domain is punished with a hot laser invisible to the fly. Each turning domain is also associated with an arena color. The lights are turned off at the last two periods. Wild type flies fail to learn to avoid the punished domain after the training periods in these conditions. A positive PI-score in the 12th period indicates that the fly learned.

Yaw torque experiments with Nlg2-gRNA lines

on Monday, June 22nd, 2026 12:15 | by

Summary lab work

on Tuesday, June 9th, 2026 12:59 | by

MBON Screen progress 01.06.2026

on Monday, June 1st, 2026 12:59 | by

MBON screen progress 26.05.2026

on Tuesday, May 26th, 2026 9:05 | by

MBON screen progress 18.05.2026

on Monday, May 18th, 2026 12:32 | by

PI- values for world learning torque experiments. As usual the flies were tethered and subjected to adverse stimuli by laser dependent on torque domain, which also controlled arena color. Flies that show positive PI at the end indicate premature habit formation as WT flies don’t learn under these conditions in this time frame.
Same as above except the pretest preference has been subtraced
Current p-values for all the tested groups. Should be 25-30 flies at trial end.

MBON screen progress 11.05.2026

on Monday, May 11th, 2026 12:25 | by

Results from premature habit formation torque measurements of four drosophila crosses: MB399B, MB050B & MB027B gal4 driver lines crossed with UAS-Tetanus toxin lines and Wild type Berlin crossed with UAS-TnT as control. Which line is which is still unknown as the screen is incomplete and researcher must remain blind. It appears two crosses strongly form habits prematurely, one doesn’t and one is still on the borderline.

PI-values subtracted:

Same results as above except with pretest bias subtracted.

p-values:

p-values for the different groups

Summary molecular work

on Monday, March 30th, 2026 12:54 | by

Long form habit formation pooled data 16-20th & 23-27th of March 2026

on Monday, March 30th, 2026 12:07 | by

Performance index values for long sequence habit formation trial

Habit formation long, 15.3-20.3.2026

on Monday, March 23rd, 2026 10:33 | by

Results from week 15-20.3.2026 of the long form habit formation trial. Only 6 flies out of 24 managed to successfully complete the trial. Avoidance was improved by increasing laser voltage.