Final JoyStick results from Alisa’s trials
on Monday, August 4th, 2025 1:53 | by Daniel Döringer
Control groups fed with ATR (Gr28bdTrpA1_Suc_ATR and Gr28bdTrpA1_Suc_ATR) look fine and for now the avoidance by activating heat sensing neurons does not seem to depend on dopamine. The negative control (Gr28bdTrpA1_Suc_EtOH) shows stronger avoidance than we would expect. Also PIs of PPM2 lies do not follow the same pattern as we previosly observed… My current hypothesis is that some sort of mutation led to the Chrimson channel being more sensitive to light, even without ATR. Since we rear the PPM2 flies in light until they receive the ATR this might affect their behavior.

Luisa’s results for yellow light:

Category: Optogenetics
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