Heat shock rescue of tßh-gene in Buridan’s paradigm

on Thursday, November 29th, 2012 12:50 | by Christine Damrau

The loss of tßh in adult flies leads to decreased walking speed and an increase in stripe fixation. Rescuing the gene by a heat shock construct (flies from Henrike Scholz, Cologne) increases walking speed back to wild type level but cannot change stripe fixation.

It is possible that the phenotype in stripe fixation is not exclusively tßh-dependent but more due to other problems the tßh-mutants have, e.g. developmental defects. That would ask for another heat shock timing.


–          1st cross














–          2nd cross