FoxP locus + translations

on Wednesday, May 13th, 2020 2:32 | by Ottavia Palazzo


We understood that due to a stop codon in the intron 7 sequence, the Isoform-IR can not be translated until the end. The FH domain in the Isoform-IR is not complete, due to the fact that the intron do not participate in it. It’s thus likely that the IR is not acting properly as a transcription factor since the DNA binding domain is not complete.

Category: Foxp

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