The what and where of operant self-learning

In the last couple of years, we have shown that world-learning (the process assigning value to sensory stimuli) and self-learning (the process assigning value to a specific action or movement) were two components of operant learning. The two elements depend on different molecular substrates and they interact: world-learning inhibits the formation of self-learning.
This project aims to decipher the molecular bases of self-learning using the genetic tools available in Drosophila in combination with behavioral read-outs. We know that an inhibitor of PKC prevents self-learning formation. The main goals are to identify which PKC is involved in this behavior and where it is involved in the fly brain.

News concerning this project

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